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Lira Clinical Launches REGEN Line With Wild Salmon Stem Cell Innovation

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The Lira Clinical REGEN PDRN+ Crème bottle stands beside the REGEN PDRN+ Serum dropper bottle on a white background.
Photo courtesy of Lira Clinical.

Lira Clinical has announced REGEN, a new line the company describes as the first and only clinical skin care line formulated with Wild Salmon Stem Cell Conditioned Media. The company says the ingredient delivers more regenerative power than PDRN alone. The line was developed in collaboration with Wildtype and is built for what the brand calls PROAging skin care and its emerging category of Clinical Brightening.

The conditioned media, also called Marine Cellular Complex, sits at the center of the formulas. Lira Clinical says the complex contains nearly 2,000 different bioactive growth factors, salmon derived exosomes, thousands of peptides, antioxidants and stem cells that promote collagen repair and structural support while visibly reducing redness and inflammation. In the REGEN formulas, the complex is combined with PDRN and Copper Tripeptide 1 to promote healthier and brighter skin by supporting hydration, circulation and firmness. A proprietary phospholipid encapsulation technology carries the active ingredients deep into the skin, the company says, without damaging its protective barrier.

REGEN arrives in two formats. REGEN PDRN+ Serum combines the conditioned media with PDRN and Copper Tripeptide 1, and the company calls it the first and only serum in the clinical market to do so. REGEN PDRN+ Crème is a volumizing formulation made to restore skin density, improve structure and extend the brightening benefits of the line. Both formats were formulated for professional treatments and for home use, and the line is available through Lira Clinical professional channels and international distributors worldwide.

“Lira Clinical’s core values have always been about real people, real results, with more clinical studies to come,” said Metaxia Dalikas, cofounder and chief executive officer of Lira Clinical. “PDRN is a buzzword now, but Lira is the first company to introduce wild salmon stem cell conditioned media that now goes beyond the benefits of PDRN.”

Wildtype, the San Francisco based cultivated seafood company behind the complex, is expanding into skin care with the launch. The company says its complex is grown from salmon cells rather than actual salmon, in a process it describes as animal free and ocean positive, and that the complex is made from 15,540 peptides and 5,105 proteins.

We Speak Beauty

Bobbi Brown Teams With The Met for a Holiday Makeup Collection Wrapped in Masterpieces

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Bobbi Brown x The Met holiday makeup, including an open eye shadow palette, blush, lipsticks and a balm with artwork packaging, arranged with a red ribbon.
Photo courtesy of Bobbi Brown.

Bobbi Brown has joined forces with The Metropolitan Museum of Art for a limited edition holiday makeup collection that puts masterworks from the museum onto the vanity. Each product pairs a signature Bobbi Brown formula with a specific work of art from The Met collections of European Paintings and of Drawings and Prints, chosen for the harmony between the palette of the painting and the finish of the product. A first phase of the collection is available now, with additional drops releasing globally on November 12, 2026.

The centerpiece is an eye shadow palette of eight shades in matte and shimmer finishes, priced at $72, with each pan at 0.04 oz and 1.3 g. Its compact carries a detail from Landscape with Stars, painted by Cross between 1905 and 1908, set in the signature gilded frame of the brand, with a pressed design on four of the shades. The same painting appears on the Luxe Shimmer Eyeshadow in Rose Illusion, a rose gold shade with gold sparkle, priced at $45.

For the face, the Brightening Blush is a three in one multidimensional blush priced at $52, offered in Blushed Peach and Blushed Burgundy. Its compact features a detail from Mäda Primavesi by Gustav Klimt, painted in 1912 and 1913. For lips, the Luxe Lipstick case carries a detail from Pandora by Odilon Redon, painted in 1914, and the Extra Lip Tinted Balm, priced at $39, features Bouquet of Sunflowers by Claude Monet, painted in 1881. The balm gives sheer color that blooms as it adjusts to the pH of the lips, with hydrating and plumping benefits.

Global Pro Artist Cassandra Garcia created the looks for the collection. “I love this collection because it’s so iconic yet effortless,” Garcia said. “The shades are beautiful and so versatile. You can go soft and neutral or bold and dramatic with eyes and lips, and brighten any look with a touch of cheek color.”

The Bobbi Brown x The Met collection is sold at bobbibrowncosmetics.com and at Bobbi Brown counters, and the brand presents the pieces as collectible holiday gifts that earn their place on the vanity long after the season ends.

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